Great Ormond Street Hospital for Children NHS Foundation Trust

The GOSH pharmacy team are on a journey to build their research portfolio and embed research expertise in their team. 🔬 In 2023/24 they were involved in the publishing of over 50 publications and abstracts and set up the London Paediatric Research Network, an opportunity to bring together pharmacy teams from across London to discuss and share learnings. The Children’s Medicines Research & Innovation Centre (CMRIC) is crucial to this work and aims to embed research and clinical expertise into the team. Find out more: https://lnkd.in/ed4srjSA

Our Biomedical Research Centre is a collaboration between GOSH and UCL Great Ormond Street Institute of Child Health. Funded by the NIHR (National Institute for Health and Care Research), it’s the leading children’s medical research centre in Europe. It provides cutting-edge facilities and world-leading expertise that allows our staff and NHS, university and industry collaborators to conduct pioneering research into potential treatments for rare and complex diseases in children. Watch our video to find out more about the centre and what it does to support our patients and staff.

We are wishing the best of luck to all our young transplant patients, donors and their families who are competing in the British Transplant Games in Oxford this weekend. 🏅 Across our two teams, heart & lung and renal, we have 37 patients who have had had a heart, lung or kidney transplant at GOSH. They are joined by family and GOSH staff members which brings the number of team GOSH participants up to 180, that’s our biggest team ever! 🎉

In case you missed it... 🔬    A new groundbreaking study has revealed important clues into what is driving arthritis in children.    In a world first, tiny tissue samples were taken from children whilst they underwent treatment for arthritis and were analysed with advanced imaging and gene-profiling technologies.    Detailed maps of the joints revealed differences between children of different ages and cell changes in those with more severe disease.  These unique cellular fingerprints may help researchers understand why some treatments work better for some children, and not others.     They also found that the joints of children with arthritis looked significantly different when compared to adults with arthritis, demonstrating the need to understand the condition in children better.    Albert was one of the children who took part in the study. Read his story below. 💫 

An opportunity has arisen to join our Immunology Team as a Biomedical Scientist (newly qualifying). For further information and how to apply, please visit our careers page: https://lnkd.in/eF2ziDzh

A Research Medical Laboratory Assistant opportunity has arisen to join our Histopathology Service. For further information and how to apply, please visit our careers page: https://lnkd.in/eF2ziDzh

Innovation at GOSH💡🔢 The Great Ormond Street Hospital DRIVE unit is our hub for digital innovation. It aims to use data and technology to better support our staff and improve outcomes and experience for children and young people.  Click through below for some DRIVE projects in numbers. 👇

We’re so thrilled to say that Elizabeth Ralph completed her PhD this month – she’s the first Healthcare Scientist to have been fully supported by a fellowship from our NIHR (National Institute for Health and Care Research) GOSH Biomedical Centre (BRC) and we couldn’t be prouder – well done Dr Ralph! 👏✨ GOSH is working to grow the number of professionals from different backgrounds getting PhDs and embedding research and innovation into our hospital. More about one of our newest Drs: 🩸 Liz has worked as a Clinical Scientist at GOSH for 14 years and first became interested in the area of childhood arthritis almost 10 years ago when working with Lucy Wedderburn and her team to introduce a blood test into routine use that would help predict how children would respond to treatment 🗓️ Liz’s fellowship from the BRC allowed her to take time away from her role as a Clinical Scientist at GOSH to explore her ideas on how we can better understand childhood arthritis part-time from August 2020 to December 2024 🦠 In her PhD research, Liz investigated immune cells called regulatory T cells (Treg) that build up in the joints of children with arthritis 🧬 Using detailed genetic analysis, Liz identified and characterised cells within the Tregs in the joints of children with arthritis that have features of another immune cell type called T peripheral helper cells (Tph) 💥 This has implications for potential treatment options for children with arthritis because it could be part of why Treg cells in childhood arthritis cannot control the inflammation of joints 🔗 Liz also found a link between T cells carrying a protein called CD161 and childhood arthritis, paving the way for further work to help us predict which treatments will be best for each child ✈️ Liz recently jetted off to Peru to celebrate her huge achievement for a well-deserved break Liz is keen to bring more Healthcare Scientists into the research world: “If any Healthcare Scientist colleagues are considering pursuing a PhD, particularly those thinking of doing it part-time or with caring responsibilities, then please do get in touch… I am happy to share my experiences.” #BePartofResearch

We recently had a visit from the GRAMMY-Award winning Los Angeles Children’s Chorus, as their Young Men’s Ensemble sang to our patients, families, and staff in the cove. 23-person strong chorus sang a range of uplifting music which featured songs such as ‘What was I made for?’ by Billie Ellish, Apple Tree by Aurora Aksnes and City Called Heaven by Trad Gospel, along with many other amazing songs. It was a great part of the weekend for the hospital. Thank you to Los Angeles Children’s Chorus for the fantastic performance!

This weekend a group of our brilliant GOSH colleagues including our CEO Matthew Shaw will be taking on a team of social media stars, youtubers, former footballers and celebrities in aid of Great Ormond Street Hospital Charity💙 Best of luck to all of those taking part in the match at Bromley FC on Sunday! If you are interested in attend you can grab your ticket here - https://lnkd.in/eNcVkQkZ